Localization of the Stress Proteins aB-Crystallin and Trabecular Meshwork Inducible Glucocorticoid Response Protein in Normal and Glaucomatous Trabecular Meshwork
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چکیده
RESULTS. In normal eyes, labeling for aB-crystallin occurred in the subendothelial region of Schlemm's canal and outer corneoscleral regions, whereas TIGR labeling was found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, labeling for aB-crystallin and TIGR occurred in more regions of the meshwork and appeared more intense than in normal eyes, regardless of the type or clinical severity of glaucoma.
منابع مشابه
Localization of the stress proteins alpha B-crystallin and trabecular meshwork inducible glucocorticoid response protein in normal and glaucomatous trabecular meshwork.
PURPOSE To examine the differential staining of two potential stress-response markers, alpha B-crystallin and the trabecular meshwork inducible glucocorticoid response protein (TIGR), in meshwork from normal and glaucomatous human eyes. METHODS Trabecular meshwork from 35 eyes from 23 donors with either primary open-angle glaucoma, pseudoexfoliative glaucoma, or low-tension glaucoma, and from...
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تاریخ انتشار 2005